Top Quality Synthetic Anti Cancer Pnc-27 Peptide Pnc27

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: HB-Pnc-27
• Certification: GMP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Product Name: Pnc-27
• Appearance: White Powder
• CAS: 1159861-00-3
• Mf: C84h128n18o24
• MOQ: 10vials
• Sample: Available
• Test Method: HPLC
• Shelf Life: 2 Years
• Certificate: COA/MSDS/Co
• Shipping Method: EMS/FedEx/TNT/DHL
• Delivery Time: 7-10days
• Storage: Cool Dry Place
• Package: 10mg/Vial; 10vials/Box
• Transport Package: 10mg/Vial; 10vials/Box
• Specification: 99%
• Trademark: Herben
• Origin: China
• Production Capacity: 5000boxes/Month

Product Description

Top Quality Synthetic Anti Cancer Pnc-27 Peptide Pnc27 

Product Description

 

Product Name	PNC-27
Other Name	Aviptadil Acetate
CAS NO.	1159861-00-3
Appearance	White freeze-dried powder
Purity	98% HPLC
Application	Research peptides
Shelf Life	24 Months
Storage	Store at a temperature of 2-8 degrees, protected from light.

 

PNC-27 is a membrane-active peptide that binds to the HDM-2 protein expressed in the cancer cell membranes of solid tissue tumor cells and induces transmembrane pore formation in cancer, but not in normal cells, resulting in tumor cell necrosis that is independent of p53 activity in these cells. 

PNC-27 is a peptide that contains p53 protein amino acid residues 12-26 of its HDM-2 binding domain attached to a transmembrane-penetrating sequence, also called the membrane residency peptide (MRP). Both PNC-27 and PNC-28 (which has a sequence that is identical to that of PNC-27 but lacks the first six amino acid residues of PNC-27 (i.e., p53 residues 17-26) are lethal to a wide variety of cancer cells with IC50 values ranging from around 75 ug/ml (18.6 uM) to 200 ug/ml (50 uM). On the other hand, neither peptide affects normal or untransformed cells in culture, including human hematopoietic stem cells even at the highest doses (around 500 ug/ml) tested. The latter finding suggests that both peptides would not be toxic to bone marrow function in contrast to the effects of many chemotherapeutic agents.
 

Packaging & Shipping

Packaging Details:
1. Usually in bare bottle packaging;
2. 5mg/10mg/15mg per vial, 10vials/box;
3. The outer packaging is usually a white cardboard box without any label;
4. We can provide customization services; 5. Generally,a maximum of 25boxes can be sent per package.
Delivery Detail:
Within 3 days when get the payment. 
Shipping:
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR.

Company Profile

 

Our Advantages

Top Quality

Using high quality material and establishing a strict quality control system, assigning specific persons in charge of each part of production, from raw material purchase to assembly.

Professional R&D Center

Employed researchers with 15 years working experience in plant extraction industry. Each month will release a new series of products.

Fast Dispatch

Most of the products are in stock. Quality below 100kgs can be deliveredwithin 5-7 days.

Price Advantage

Low MOQ with competitive price.

Online Service

Professional team 7x24hours customer service.

OEM/ODM Service

GMP factory OEM and ODM generation processing are warmly welcomed.

Q1: Can l get some free sample for a test?

A:Yes, we can offer small quantity free sample for your test if you can pay for the shipping cost or freight collect.

Q2: What's your MOQ ?

A:Our minimum order quantity is 10vials. But usually we accept less quantity of some special and expensive products,you can contact us for more information.

Q3:How about delivery time?

A:Within 5~7 working days by Express.

Q4: ls there any discount?

A:Different quantity has different discount, the more you buy, the more you will save.

Q5:How do you treat quality complaint?

A:First of all, our quality control will reduce the the quality problem to zero. lf any questions, we will send you free goods again or fully refund you.

Q6:How to contact us?

A:You can choose your interested products and send an inquiry to us. You can dialour telephone directly, write email to us, we will reply you as soon as possible.