Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Powder |
Purity: | >99% |
Samples: |
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Customization: |
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Product Name
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Pharmaceutical Intermediate with Semaglutide CAS 99291-20-0 |
CAS NO
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910463-68-2
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Appearance
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White Powder
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Molecular Formula
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C187H291N45O59
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Storage
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Keep in a cool, dry, dark location
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Shelf Life
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24 months when properly stored
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Semaglutide is a new generation GLP-1 (glucagon-like peptide-1) analogues. Semaglutide is a long-acting dosage form based on the basic structure of liraglutide, which is more effective in the treatment of type 2 diabetes mellitus. Compared with lilarlutide, somalutide has a longer aliphobic chain and an increased hydrophobicity, but somalutide is modified with a short chain of PEG, and its hydrophilicity is greatly enhanced.PEG modification can not only tightly bind to albumin, cover up the DPP-4 enzymatic hydrolysis site, but also reduce renal excretion, prolong the biological half-life, and achieve the effect of long circulation.
Semaglutide (USAN; trade name ) is a pharmaceutical drug in development by a Danish company Novo Nordisk for the treatment of type 2 diabetes. It is marketed by the name As a glucagon-like peptide-1 receptor agonist, it lowers the blood sugar level by increasing the production. It was discovered in 2012, by a team of researchers at Novo Nordisk as a longer-acting alternative to liraglutide. Clinical trials were started in 2015, and phase 3 was completed in 2016. FDA approval was applied in December 2016, and in October 2017 FDA Advisory Committee voted 16-0 in favour. It can be used as both injection-type or oral-type drug.
Researchers at the University of Leeds reported in 2017 that it can also be used for the treatment of obesity. It reduces hunger, food craving and body fat.
Test Items
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Specification
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Test Results
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Appearance
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white or almost white crystalline powder, slightly smelly
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white crystalline powder
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Melting point
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123~127°C
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123~125°C
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Specific Rotation
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+28°~+30°
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+29°
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Acidity(PH)
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5.2~6.5
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5.8~6.2
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Water
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4.0%~5.5%
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5.0%
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Residue On Ignition
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Not more than 0.1%
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Conforms
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N.N - dimethylaniline
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Comply with the standard
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Conforms
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Phenolic Compounds
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Comply with the standard
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Conforms
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Related Substance
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Comply with the standard
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Conforms
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Assay
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Between99.0~102.0%
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99.53%
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Conclusion
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This batch is complies with USP 34.
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Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging ;
aluminium bag outside and double plastic bag inside;
Delivery Detail:
Within 3 days when get the payment.
Shipping:
We have Professional shipping agent, based on customers ' demand for transport
By express: FEDEX, DHL, EMS, UPS, TNT ect.
By SEA and By AIR.
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FeDex will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers.The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, Western Union, Money Gram, Paypal.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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