Fast Delivery CAS 910463-68-2 Treatment Obesity Semaglutide

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: Semaglutide
• Product Name: Semaglutide
• CAS: 910463-68-2
• Mf: C187h291n45o59
• MOQ: 1box
• Assay: 99%
• Certificate: COA/MSDS/Co
• Test Method: HPLC
• Stock: in Stock
• Sample: Available
• Delivery Time: 7-9 Days
• Shipping Method: EMS/FedEx/TNT/DHL
• Transport Package: 1 Box
• Specification: 99%
• Trademark: Herben
• Origin: China
• Production Capacity: 1000

Product Description

 

Product Description

 

 

Product name	Semaglutide
CAS number	910463-68-2
Molecular formula	C187H291N45O59
Molecular weight	4113.57754

 

Semaglutide is a new generation GLP-1 (glucagon-like peptide-1) analogues. Semaglutide is a long-acting dosage form based on the basic structure of liraglutide, which is more effective in the treatment of type 2 diabetes mellitus. Compared with lilarlutide, somalutide has a longer aliphobic chain and an increased hydrophobicity, but somalutide is modified with a short chain of PEG, and its hydrophilicity is greatly enhanced.PEG modification can not only tightly bind to albumin, cover up the DPP-4 enzymatic hydrolysis site, but also reduce renal excretion, prolong the biological half-life, and achieve the effect of long circulation.

Semaglutide (USAN; ) is a pharmaceutical drug in development by a Danish company Novo Nordisk for the treatment of type 2 diabetes. It is marketed . As a glucagon-like peptide-1 receptor agonist, it lowers the blood sugar level by increasing the production. It was discovered in 2012, by a team of researchers at Novo Nordisk as a longer-acting alternative to liraglutide. Clinical trials were started in 2015, and phase 3 was completed in 2016. FDA approval was applied in December 2016, and in October 2017 FDA Advisory Committee voted 16-0 in favour. It can be used as both injection-type or oral-type drug.
Researchers at the University of Leeds reported in 2017 that it can also be used for the treatment of obesity. It reduces hunger, food craving and body fat.

 1. For Type 2 diabetes
Semaglutide has been widely used for type II diabetes because of its role in promoting secretion, inhibiting glucagon secretion, delaying gastrointestinal emptying and improving  sensitivity.
It can promote the secretion thereby lowering blood sugar.

Glucagon is one of the important factors in the rise of blood sugar, and semaglutide vial powder can also inhibit the secretion of glucagon, thereby reducing the rise of blood sugar.
It can control blood sugar by delaying gastrointestinal emptying and slowing the rate at which food is converted into glucose.
It can improve the body's sensitivity to, reduce  resistance, and thus control blood sugar.
It can reduce the total intake of calories by suppressing the central nervous system of appetite, which helps to control weight and further control blood suger.

Notes: Used of semaglutide needs to be carried out under the guidance of a doctor, and attention should be paid to side effects and contraindications.



2. Lose weight

Semaglutide promotes the secretion of GLP-, a gastrointestinal hormone that stimulates visual neurotransmission and the appetite center of the brain, thereby increasing satiety and reducing food intake.

It can also produce appetite suppression effect by inhibiting the hunger center in the brain, reducing appetite, and then controlling weight.

It is able to reduce the body's  resistance and prevent excessive accumulation of glucose in the body, which promotes lipolysis and reduces body fat mass.

Previous studies have shown that GLP-1 receptor agonists can improve the body's metabolic rate and accelerate the body's energy consumption, so the weight loss effect of semaglutide vial powder is very good..

Notes: Use of semaglutide needs to be carried out under the guidance of a doctor, and with reasonable diet and exercise, in order to achieve good weight loss results.

Specification

 

Certificate of Analysis
Product Name	Semaglutide	CAS NO.	910463-68-2
Salt Type	Na^+	Manufacturing Date	2023.04.22
Sequence	His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEE γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Storage	Stable at 2-8ºC,but should be kept at-20ºC for long term storage,preferably desiccated.
ITEM	SPECIFICATION	RESULTS
Appearance	White or off-white powder	Conforms
Solubility	Soluble in H2O	Conforms
Amino acid analysis	His (0.9-1.1) Asp(0.9-1.1) Ala(2.7-3.3) Val(1.8-2.2) Glu(4.5-5.5) Leu(1.8-2.2) Gly(3.6-4.4) Lys(0.9-1.1) Thr(1.8-2.2) Phe(1.8-2.2) Arg(1.8-2.2) Ser(2.7-3.3) Ile(0.9-1.1) Tyr(0.9-1.1) Aib(0.8-1.2) AEEA(1.6-2.4) Trp(Det)	His 1.0 Asp 1.0 Ala 3.2 Val 3.2 Glu 5.2 Leu 2.0 Gly 4.2 Lys 1.0 Thr 2.0 Ile 1.1 Phe 1.9 Arg 2.1 Ser 2.8 Tyr 1.1 Aib 1.0 AEEA 2.0 Trp(Det)
Purity	≥98.0%	99.28%
Mass Spectrum	4113.58±1.0	4113.8
Clear and color of solution	Clear and colorless	Conforms
Water	≤8.0%	2.50%
Thifluoroacetate ion	≤0.1%	N.D
PH	6.0-9.0	6.94
Sodium ion	≤4.0%	1.20%
Phosphate ion	<0.5%	N.D
Chloride ion	<0.5%	N.D
Related Dubstances(HPLC)	Any indivial impurity:≤1.0% Total impurity:≤2.0%	0.30% 0.72%
Peptide Assay	≥85.0%	95.58%
Bacterial endotoxin	<10EU/mg	Conforms
Conclusion	The test results comply with the requirements of in-house specification.

 

Packaging & Shipping

Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging ;
aluminium bag outside and double plastic bag inside;
Delivery Detail:
Within 3 days when get the payment. 
Shipping:
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR.

Company Profile

 

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FAQ

Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.

Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FeDex will be 3~5 days to you.

Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.

Q4. Can you supply the free sample?
A: Usually it is possible. It based on the different product. Please be free to consult our salesman.

Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers.The shelf life will be 2 years.

Q6: What's your main payment method?
A: T/T, Western Union, Money Gram, Paypal.

Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.