| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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High Purity Nsi-189 CAS 1270138-41-4 with Best Price Phosphate Powder
| Product Name | NSI-189 |
| Synonyms | NSI-189 H3PO4;NSI-189 phosphate;(4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl] |
| CAS | 1270138-41-4 |
| MF | C22H33N4O5P |
| MW | 464.494981 |
| Usage | NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine |
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.IC50 value:Target: in vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].in vivo: NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20%
Tests have shown that NSI-189 significantly improved behavioral responses that are associated with depression . In humans it may counter hippocampal atrophy which is seen in disorders such as MDD, reversing their symptoms. A phase 1B randomized, double-blind, placebo-controlled, multiple-dose escalation study conducted over a 28 day period showed behavioral efficacy in 24 patients who were orally administered NSI-189 . The efficacy measurements showed a clinically meaningful reduction in cognitive and depressive symptoms across all measures, and appeared to persist over time during follow up for the efficacy assessments which included the Clinical Global Impression - Improvement (CGI-I), Montgomery-Aserb Depression Rating Scale (MADRS), Cognitive and Physical Functioning Questionnaire (CPFQ, and the Symptoms of Depression Questionnaire (SDQ) .
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Product name |
NSI-189 |
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| CAS No. |
1270138-40-3 |
Outer Packing | |
| Production date |
Dec. 15. 2016. |
Shelf life |
Dec. 14th. 2019 |
| Standard adopted |
in-house standard |
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| Items of analysis | Specification | Results | |
|
Appearance |
Off-white powder |
Confrom |
|
|
Identification |
IR and HPLC spectrum shall conform to the standard sample |
conform |
|
|
Melting Point |
83ºC~86ºC |
84.3ºC~85.6ºC |
|
|
Loss on Drying |
Less than 0.5% |
0.29% |
|
|
Purity(On Dried Base,HPLC) |
NLT 99.5 % |
99.62% |
|
|
Total Impurity |
Less than 0.5% |
0.33% |
|
|
Residue On Ignition |
≤0.2% |
0.16% |
|
|
Heavy metal |
≤20ppm |
conform |
|
| Conclusion | Qualified | ||
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging ;
aluminium bag outside and double plastic bag inside;
Delivery Detail:
Within 3 days when get the payment.
Shipping:
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR.
Xi'an Bpanda Biological Technology Co., Ltd was established in Xi'an. Registered capital is 1 million. It is a comprehensive company providing biotechnology services, consulting and product sales. Its main products are cosmetics, health products, plant extracts, food additives and chemical products.
Bpanda aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier.
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FeDex will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers.The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, Western Union, Money Gram, Paypal.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one
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