| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
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| Customization: |
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Audited Supplier 
| Product Name | Tianeptine sodium |
| MW | 436.95 |
| Mol File | 66981-73-5.mol |
| Product Categories | pharmaceutical intermediate |
| Appearance | Powder, insoluble in water |
| Application | It may be used for pharmaceutica; For lab research |
| PackAge | in 25kgs plastic drum, 20mts/20'fcl |
| Purity | >99% |
| Storage | stay in dry, cool and well-sealed |
Tianeptine has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in elderly patients and in those following alcohol withdrawal; such patients can be more sensitive to the adverse effects of psychotropic drugs. Recent interesting results indicate anticonvulsant and analgesic activity of tianeptine and its possible interaction with adenosine A1 receptors.
Tianeptine is neuroprotective via multiple neurochemical and cellular mechanisms. In theory, tianeptine's neuroprotective action makes it a potential life-extension drug. When an organism is under stress, or perceives itself under stress, the hypothalamus secretes corticotropin-releasing hormone/factor (CRH/CRF). CRH/CRF in turn increases secretion of adrenocorticotrophic hormone from the anterior pituitary. in turn stimulates the release of glucocorticoids from the adrenal cortex. Persistent, uncontrolled physical and psychosocial stress causes excess cortisol secretion from the adrenal glands. Excess cortisol causes dendritic shrinkage in the hippocampus and a contrasting growth of dendrites in the lateral amygdala. These stress-induced changes tend to lower mood; they can cause clinical depression in the genetically vulnerable. Current evidence suggests that tianeptine acts to prevent and even reverse stress-induced neural damage, promoting both neuronal survival and synaptic plasticity.
It is widely used to treat mild to moderate depression. It improves mood and mental state and reduces symptoms of depression by regulating the level of the neurotransmitter 5-hydroxytryptamine (5-HT) in the brain.
| Items | Specification | Result |
| Tianeptine Sodium | 99% | 99.02% |
| Organoleptic | ||
| Appearance | Fine Powder | Conforms |
| Color | White powder | Conforms |
| Odor | Characteristic | Conforms |
| Taste | Characteristic | Conforms |
| Physical Characteristics | ||
| Particle Size | NLT 100% Through 80 mesh | Conforms |
| Loss on Drying | <=12.0% | Conforms |
| Ash (Sulphated Ash) | <=0.5% | Conforms |
| Total Heavy Metals | ≤10ppm | Conforms |
| Microbiological Tests | ||
| Total Plate Count | ≤10000cfu/g | Conforms |
| Total Yeast & Mold | ≤1000cfu/g | Conforms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Staphylococcus | Negative | Negative |
1.Can I get some samples?
Yes, usually a 10-20g sample.
2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.
3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.
4. How to deliver the goods?
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.
5. What is the shelf life for the products?
Most products shelf life 24-36 months.
6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.
7. How about the validity of the offer?
Usually, our offer is valid for 1 week. However, validity might vary between different products.
Suppliers with verified business licenses
Audited Supplier 
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