High Quality and Low Price 99% Rivaroxaban CAS 366789-02-8

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Rivaroxaban
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• MOQ: 1kg
• Assay: 98%
• Sample: Available
• Shipping Method: FedEx, DHL, TNT, EMS
• Stock: in Stock
• Certificate: Co, COA, MSDS
• Application: Pharmaceutical Grade and API
• Test Method: HPLC
• Product Name: Rivaroxaban
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Herben
• Origin: China
• Production Capacity: 10000

Product Description

High Quality and Low Price 99% Rivaroxaban CAS 366789-02-8

Product Description

 

Product Name: Rivaroxaban
Synonyms: (S)-Rivaroxaban;(S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)thiophene-2-carbox;RIVAROXABAN STAGE-IV [5-CHLORO-N-({5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-1,3-OXAZOLIDIN-5-YL}-METHYL)-2(AS PER INV;5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide;BAY 59-7939;Rivaroxaban Isomer;Rivaroxaban;5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
CAS: 366789-02-8
MF: C19H18ClN3O5S
MW: 435.88
EINECS: 685-132-2

Venous thromboembolism continues to be a major health concern despite conventional anticoagulation therapies. Rivaroxaban is a recent market introduction that directly inhibits FXa with high potency (Ki=0.4 nM; IC50=0.7 nM) and selectivity>10,000-fold over other related serine (thrombin, trypsin, plasmin, FVIIa, FIXa, FXIa, urokinase, and activated protein C). From the X-ray crystal structure, the central oxazolidinone moiety anchors the drug through two hydrogen bonds to Gly219 and directs the morpholinone group into the S4 pocket and the chlorothiophene portion into the S1 pocket. These key components may be coupled together synthetically by a couple of routes. Condensation of 3-morpholinone with 4-fluoronitrobenzene followed by catalytic hydrogenation provides N-(p-aminophenyl)morpholinone for subsequent reaction with (S)-2-(phthalimidomethyl)oxirane. With establishment of the aminoalcohol adduct, cyclization with 1,1′-carbonyldiimidazole generates the central oxazolidinone. Deprotection and acylation with 5-chlorothiophene-2-carbonyl chloride affords rivaroxaban.

Rivaroxaban is recommended as an option for treating pulmonary embolism and preventing recurrent deep vein thrombosis and pulmonary embolism in adults.
1. Rivaroxaban ( Bayer) is indicated for the 'treatment of deep vein thrombosis and pulmonary embolism, and prevention of recurrent deep vein thrombosis and pulmonary embolism in adults'. For the initial treatment of acute pulmonary embolism, the recommended dosage of rivaroxaban is 15 mg twice daily for the first 21 days followed by 20 mg once daily for continued treatment and prevention of recurrent venous thromboembolism.
2. Non-Valvular Atrial Fibrillation (NVAF)* to prevent stroke & systemic embolism.
3. Acute VTE treatment & prevention of recurrent VTE [for deep vein thrombosis (DVT) and pulmonary embolism (PE)].
4. Prevention of venous thromboembolic events (VTE) in elective total hip or knee replacement surgery (THR, TKR).

Item	Test Standard		Testing Result
Appearance	Powder		Complies
Color	White fine Powder		Complies
Particle Size	100% pass 80 mesh		Complies
Oder	Characteristic		Complies
Taste	Characteristic		Complies
Loss on Drying	≤5.0%		2.20%
Residue on Ignition	≤0.1%		0.05%
Residual	≤0.1%		Complies
Residual Ethanol	≤0.5%		Complies
Heave Mentals	≤10ppm		Complies
Na	≤0.1%		<0.1%
Pb	≤3 ppm		Complies
Total Plate	<1000CFU/g		Complies
Yeast & Mold	<100 CFU /g		Complies
E. Coli	Negative		Complies
Salmonella	Negative		Complies

 

Product Name	CAS No.	Product Name	CAS No.
Albendazole	54965-21-8	Levamisole	14769-73-4
Ivermectin	70288-86-7	Triclabendazole	68786-66-3
Fenbendazole	43210-67-9	Dimetridazole	551-92-8
Mebendazole	31431-39-7	Tetramisole hydrochloride	5086-74-8
Nitenpyram	120738-89-8	Diclazuril	101831-37-2

Packaging & Shipping

Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging ;
aluminium bag outside and double plastic bag inside;
Delivery Detail:
Within 3 days when get the payment. 
Shipping:
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR.

Our Reviews

 

Company Profile

Xi'an Bpanda Biological Technology Co., Ltd was established in Xi'an. Registered capital is 1 million. It is a comprehensive company providing biotechnology services, consulting and product sales. Its main products are cosmetics, health products, plant extracts, food additives and chemical products.

Bpanda aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier.

Our Advantages

FAQ

Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.

Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FeDex will be 3~5 days to you.

Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.

Q4. Can you supply the free sample?
A: Usually it is possible. It based on the different product. Please be free to consult our salesman.

Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers.The shelf life will be 2 years.

Q6: What's your main payment method?
A: T/T, Western Union, Money Gram, Paypal.

Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one